Opportunity: Ingenuity Pathway Analysis Software License

NOTICE OF INTENT FOR SOLE SOURCE The U.S. Environmental Protection Agency (EPA), in Research Triangle Park, NC, intends to award a sole source purchase order under authority of Federal Acquisition Regulation (FAR) Part 13, Simplified Acquisition Procedures to Qiagen, Inc. to purchase Ingenuity Pathways Analysis (IPA) with Advanced Analytics Software. EPA has used the Ingenuity Pathway Software since 2004 and have generated volumes of legacy data. As such, it is required for continuity of data analyses for the comparison of newly generated contemporary data in the research project. Procurement of this software will enable comparative analyses over the entire research project. Ingenuity Pathways Analysis Software is a web-based application that enables researchers to explore, understand, and discover relevant networks significant to their research results. Using a researcher¿s gene or protein dataset in combination with Ingenuity's genome-scale knowledge base, the application generates multiple biologic networks with an associated functional analysis to facilitate biological understanding of the dataset. Specifically it: A. Supports genomic and proteomic data analysis B. Enables discovery of novel genes, proteins and interactions (canonical) pathways C. Allows expansion of pathways to identify putative targets D. Contains manually curated pathways from full-text scientific literature (not just abstracts) E. Allows comparisons of 2 groups of pathways F. Allows user creation of a pathway from a set of genes G. Develops pathways from an input gene list on the "fly", meaning it develops a pathway from just that set of genes and no others This is a unique Pathway Analysis software that allows researchers to view their data in terms of networks of pathways in an "interactomic fashion." There are no pathway analysis packages on the market today that contains the depth of annotated pathways as provided by Ingenuity Pathway Software. The circumstance permitting is FAR 13.106-1(b) "Soliciting from a single source". All interested parties who believe they can provide the required services should fully explain their capabilities and qualifications in writing within 7 days from the date of this announcement and provide itemized pricing that is sufficient to make a determination that competition is feasible. The intent of this notice is to determine if any other source(s) exist, and therefore, no solicitation is available. Consequently, anyone failing to provide the aforementioned and instead chooses to merely submit a routine letter requesting a copy of the statement of work or more information about the project will be ignored. The information received to this notice will be considered solely for the purpose of determining whether or not to conduct a competitive procurement. Please submit response ONLY to Sammie Jones at jones.sammie@epa.gov. No telephone or faxed requests will be honored.