Opportunity: Systems Biology of Bioenergy-Relevant Microbes to

Description 

DOE-BER¿s Genomic Science program supports fundamental research to identify the foundational principles that drive biological systems. These principles govern translation of the genetic code into integrated networks of proteins, enzymes, regulatory elements, and metabolite pools underlying the functional processes of organisms. To address the DOE mission in sustainable bioenergy development the Genomic Science program brings omics-driven tools of modern systems biology to bear on the challenges associated with microbial production of advanced biofuels. Developing an increased understanding of how biological systems function and translating that knowledge to enhance the production capabilities of microbes and plants forms the basis of DOE¿s mission in sustainable bioenergy. To harness the biosynthetic processing power of the microbial world for advanced biofuels production, an expanded set of platform organisms with appropriate metabolic capabilities and stress tolerance characteristics will need to be developed. To hasten this development, the DOE-BER Genomic Science program supports research aimed at improving fundamental understanding of principles that govern the functional properties of bioenergy relevant organisms at the genome scale thereby enabling the development of molecular genomics approaches and computational tools for the design, construction, and validation of improved biological components and systems. This endeavor is highly interdisciplinary, spanning multiple fields in biology, systems biology, chemical and metabolic engineering, and computational biology.

Overview 
Reference number: DE-FOA-0001060
Issue date: 12/20/2013
Response due: 03/14/2014 11:59 PM US/Eastern

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Agency: DOE

Contracting office:

Office of Science - Chicago
U.S. Department of Energy
Office of Acquisition & Assistance
9800 South Cass Avenue
Argonne, IL 60439


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